11.24.2011
Robots creating scientific hypotheses
With the development of Watson, IBM showed the world what computers can do with vast text databases like Wikipedia. In Watson's case, the goal was to win at Jeopardy. Now that same kind of technology is being deployed to win at science:
Scientists are developing a computer that can read vast amounts of scientific literature, make connections between facts and develop hypotheses
Scientists are developing a computer that can read vast amounts of scientific literature, make connections between facts and develop hypotheses
At the heart of CRAB, the development of which was funded by the Medical Research Council and the Swedish Research Council among others, is a taxonomy that specifies scientific evidence used in cancer risk assessment, including key events that may result in cancer formation. The system takes the textual content of each relevant MEDLINE abstract and classifies it according to the taxonomy. At the press of a button, a profile is rapidly built for any particular chemical using all of the available literature, describing highly specific patterns of connections between chemicals and toxicity.
“Although still under development, the system can be used to make connections that would be difficult to find, even if it had been possible to read all the documents,” added Dr. Korhonen. “In a recent experiment, we studied a group of chemicals with unknown mode of action and used the CRAB tool to suggest a new hypothesis that might explain their male-specific carcinogenicity in the pancreas.”
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